Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and the ability of a biological system to readily detoxify the reactive intermediates or repair the resulting damage. Disruptions in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids and DNA. Oxidative stress from oxidative metabolism causes damage to bases, as well as breaks in DNA. Damage to bases is usually indirect and is caused by the reactive oxygen species (ROS) generated, e.g., O2- (superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). Furthermore, some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling.
In humans, oxidative stress is believed to be involved in the development of ADHD, cancer, Parkinson's disease, Lafora's disease, Alzheimer's disease, atherosclerosis, heart failure, myocardial infarction, fragile X syndrome, sickle cell disease, lichen planus, vitiligo, autism , infection, chronic fatigue syndrome (ME/cvs) and depression and appears to be characteristic of individuals with Asperger's syndrome. However, reactive oxygen species can be beneficial because they are used by the immune system as a way to attack and kill pathogens. Short-term oxidative stress may also be important in preventing aging through induction of a process called mitohormesis.
Treatment BeterKlinic
BeterKliniek is the clinic for Integrative Medicine that bridges regular and non-regular medicine.
An van Veen (physician) and Michael van Gils (therapist) look for the cause of a condition or disease. That is where the treatment starts otherwise, as people often say, it is 'carrying water to the sea'. We call this cause medicine. Sometimes it is also desirable to treat the symptoms (at the same time). We call this symptom medicine.
Chronic disorders often have their cause in epi- genetics. You can schedule a free informative telephone consultation (phone number 040-7117337 until 1 p.m.) at BeterKliniek to discuss your symptoms so that we can provide you with further advice.
